POLYPHENOLIC COMPOUNDS INHIBIT PANCREATIC CANCER

POLYPHENOLIC COMPOUNDS INHIBIT PANCREATIC CANCER

Polyphenolic procyanidins are flavonoid polymers composed of flavan-3-ol units (catechin and epicatechin). They are found in abundance in various products derived from cocoa bean, including cocoa, cocoa powder, and chocolate. Normally they are found at their highest concentrations in dark chocolate. It is well documented that cocoa and chocolate polyphenolic polymers are among the richest sources of procyanidins.
In vivo studies in mice using polyphenols revealed that pancreatic cancer cells selectively underwent apoptosis while non-diseased tissue was unaffected. Experimental evidence has revealed NF-kB, PI 3-kinase and ROS-generators as cell survival targets that are attenuated in this approach. In contrast, the mitochondrial permeability transition pore and caspases have been identified as molecular targets that are responsible for triggering apoptosis. This discovery can potentially be used for the treatment of other cancers, as well as for sensitizing refractory tumors to chemotherapeutic and/or radiation therapies.

ADVANTAGES

* A combination of polyphenols and ROS inhibitors dramatically reduces tumor size and inhibits tumor metastasis in a pancreatic cancer mouse model.
* The polyphenol rottlerin is effective without added ROS inhibitors.
* Non-diseased tissue is unaffected in in vivo studies in mice.
* There is no immunological response since cells die via apoptosis.
* There is no apparent toxicity.

APPLICATIONS

* Potential treatment for pancreatic cancer.
* Potential to sensitize refractory cancer cells to other treatments.
* May be applicable to other cancers.
* Possible utility as a preventative for pancreatic cancer.

Research is indicating that not only is eating dark chocolate a good strategy for preventing pancreatic cancer, but also a host of other degenerative diseases brought on by our life styles, unhealthy environment, and the foods we ingest. All chocolate is not the same.

HEALTH BENEFITS

It is well documented that cocoa and chocolate polyphenolic polymers are among the richest sources of procyanidins. It is one of the most complex food substances on earth containing over 300 chemically identifiable compounds. These beans are packed with potent antioxidants called flavonoids which boost numerous health benefits, reduce blood pressure, and decreases the body's inflammatory immune responses (which contribute to atherosclerosis).

COMPARED TO WHAT?

When a dark chocolate bar states 70% cocoa on the label it does not mean it is rich in flavonoids or nutrients. All "store bought" chocolate is heat processed which destroys most nutrients. In addition, they often contain high calories, bad fats, chemical fillers, waxes, added sugars and caffeine plus preservatives!

THE BREAKTHROUGH PATENT

A Belgium manufacturer has patented a cold pressed technology that protects the flavonoids and other phytonutrients, producing the most nutritionally potent raw unprocessed cocoa powder available.

If you have not watched this recent news release on who has the most healthy chocolate, the following is a very informative third party validation.

XoçaiTM is in the news. Check it out.


THE OPPORTUNITY

Only MXI Corp has the worldwide exclusive rights to this patented technology!

UNIQUE PRODUCTS

MXI buys its cocoa beans from family farms on the Ivory Coast where the rugged terrain creates a bean rich in flavonoids and phytonutrients. We eliminate almost all of the fat and sugar typically found in chocolate. Besides a full spectrum of nutrient rich ingredients, XoçaiTM includes raw, unprocessed cacao, blueberries, concord grapes and nature's "complete food", the Acai berry from the Brazilian rain forest. The final product is the most potent antioxidant known to man.
Caffeine-free and Kosher.
Diabetic and Vegan friendly.
Low in calories.
No added caffeine.
High in fiber and TASTES FANTASTIC!

Enjoy XoçaiTM as a power packed nugget, a simple wafer, a decadent orange flavored bar, a delicious liquid chocolate drink, or even a meal replacement protein bar... Yes - You can actually MANAGE WEIGHT with the most sinful food on the planet!

Please visit my site and learn more.



Sincerely yours